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Tirzepatide

(Combo GLP-1/GIP RA)

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Why Choose Tirzepatide?

 

Tirzepatide represents the latest breakthrough in weight management and diabetes treatment. As a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, it offers unprecedented results for patients seeking effective, long-term solutions.

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Real Patient Success:

"I lost 45 pounds in 6 months with Tirzepatide. My energy is back, my diabetes is under control, and I feel like myself again." - Sarah M.

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Mechanism of Action

  • GLP-1 Receptor Activation: Stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, and slows gastric emptying

  • GIP Receptor Activation: Enhances insulin sensitivity and may have direct effects on fat metabolism

  • Appetite Regulation: Acts on brain receptors to reduce appetite and food intake

  • Gastric Motility: Slows gastric emptying, leading to increased satiety

 

Transformative Results

 

Diabetes Management:

  • Significant reduction in HbA1c levels

  • Improved glycemic control

  • Low risk of hypoglycemia

  • Cardiovascular benefits

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Weight Management Success:

  • Average weight loss of 15-22% in clinical trials

  • Sustained weight reduction

  • Improved body composition

  • Reduction in waist circumference

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Clinical Trial Highlights:

In the SURMOUNT trials, patients achieved an average of 20.9% weight loss at the highest dose - results that exceeded all expectations and set new standards in weight management therapy.

 

 

Administration

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Injection Sites: Thigh, abdomen, or upper arm. Rotate injection sites with each injection.

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Side Effects

Common (≥5%):

  • Nausea (12-18%)

  • Diarrhea (12-16%)

  • Vomiting (6-12%)

  • Constipation (6-7%)

  • Abdominal pain (6-9%)

  • Injection site reactions

 

Serious (Rare):

  • Pancreatitis

  • Gallbladder disease

  • Kidney problems

  • Severe hypoglycemia (when combined with insulin/sulfonylureas)

  • Thyroid C-cell tumors (theoretical risk)

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Contraindications and Precautions

 

Contraindications:

  • Personal or family history of medullary thyroid carcinoma

  • Multiple Endocrine Neoplasia syndrome type 2

  • Known hypersensitivity to tirzepatide

 

Use with Caution:

  • History of pancreatitis

  • Severe renal impairment

  • Diabetic retinopathy

  • Pregnancy and breastfeeding​​

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Disclaimer: Not Medical Advice

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The information provided herein is for informational and educational purposes only and is not intended as, nor should it be construed as, medical advice, diagnosis, or treatment. Nothing contained in this content, platform, communication, or related materials should be considered a substitute for professional medical advice, diagnosis, or treatment from a licensed healthcare provider. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment. Never disregard professional medical advice or delay in seeking it because of something you have read, heard, or accessed through this platform. Reliance on any information provided is solely at your own risk.

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