

Why is Semaglutide Your Weight Loss Solution?
Semaglutide is a groundbreaking glucagon-like peptide-1 (GLP-1) receptor agonist that has revolutionized weight management and diabetes treatment.
Originally developed for type 2 diabetes, its remarkable weight loss effects have made it the go-to choice for sustainable, medically-supervised weight management.
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Patient Success Story:
"After struggling with weight for years, Semaglutide finally gave me the control I needed. I've lost 38 pounds and kept it off for over a year." - Michael R.
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Mechanism of Action
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Insulin Secretion: Stimulates glucose-dependent insulin release from pancreatic beta cells
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Glucagon Suppression: Reduces glucagon secretion from pancreatic alpha cells when glucose levels are elevated
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Gastric Emptying: Slows gastric emptying, promoting satiety and reducing post-meal glucose spikes
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Central Appetite Control: Acts on hypothalamic receptors to reduce appetite and food intake
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Beta Cell Preservation: May help preserve pancreatic beta cell function
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Life-Changing Benefits
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Diabetes Benefits:
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HbA1c reduction of 1.0-1.8%
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Reduced fasting glucose levels
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Lower postprandial glucose excursions
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Cardiovascular risk reduction
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Low hypoglycemia risk
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Weight Management Success:
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Average weight loss of 12-15% in clinical trials
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Sustained weight reduction over 68 weeks
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Improved body composition
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Reduced visceral adiposity
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Better weight maintenance
Clinical Excellence:
The STEP clinical trial program demonstrated that 86% of patients achieved at least 5% weight loss, with many achieving transformational results of 15% or more.
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Dosing and Administration
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Injectable Form:
Rotate injection site (abdomen, thigh or back of arm) with each injection.
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Oral Form (coming soon):
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Administration: Take on empty stomach with ≤4 oz water, 30 minutes before first food/drink/medication of the day
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Side Effects
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Common (≥5%):
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Nausea (15-20%)
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Vomiting (5-9%)
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Diarrhea (8-9%)
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Abdominal pain (5-7%)
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Constipation (3-7%)
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Headache (5-6%)
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Fatigue (3-5%)
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Serious (Rare):
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Acute pancreatitis
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Gallbladder disease
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Acute kidney injury
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Diabetic retinopathy complications
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Severe hypoglycemia (with insulin/sulfonylureas)
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Thyroid C-cell tumors (animal studies)
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Drug Interactions
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Insulin and Insulin Secretagogues: Increased risk of hypoglycemia; dose reduction may be needed
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Oral Medications: May delay absorption due to delayed gastric emptying
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Warfarin: Monitor INR more frequently when initiating semaglutide
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Oral Contraceptives: Use alternative contraceptive method for 4 weeks after starting or dose increases
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Monitoring Parameters
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Blood Glucose: Regular monitoring, especially when combined with other diabetes medications
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HbA1c: Every 3-6 months
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Weight and BMI: Regular monitoring for weight management indication
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Renal Function: Baseline and periodic monitoring
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Signs of Pancreatitis: Educate patients on symptoms
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Diabetic Retinopathy: Regular ophthalmologic examinations​​
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Disclaimer: Not Medical Advice
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